COULD LOW FIBRINOGEN LEVELS BE THE WEAK LINK?

Congenital fibrinogen deficiency (CFD) is a rare inherited disorder, leading to impaired clot formation and variable bleeding severity.¹ Management focuses on maintaining adequate fibrinogen levels during acute bleeding episodes and high-risk situations, often using replacement therapy and antifibrinolytic agents.¹

Watch this video to learn about the role of fibrinogen in clot stability to prevent further bleeding.

Fibrinogen plays a critical role in blood clot formation by serving as the precursor to fibrin during hemostasis.¹

About fibrinogen and CFD

Fibrinogen is the first clotting factor to reach critically low levels during bleeding episodes.²

The clinical impact

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References

May JE, Wolberg AS, Lim MY. Disorders of fibrinogen and fibrinolysis. Hematol Oncol Clin North Am. 2021;35(6):1197-1217.
Grottke O, Mallaiah S, Karkouti K, Saner F, Haas T. Fibrinogen supplementation and its indications. Semin Thromb Hemost. 2020;46(1):38-49.